Chameleon Sequences (sliding ‘probe’ over ‘target’) (CHAMPEP-SLIDING)

This database contains information on all ‘chameleon’ peptides that have identical sequence but different conformations in proteins. In this database, the ‘probe’ peptide is of fixed length and the ‘target’ peptide is of variable length (≥ length of the ‘probe’ peptide). The fixed length starts with peptides comprising seven residues (i.e., heptapeptides). One can use this database, by specifying a heptapeptide or larger sequence, in order to identify whether it is a ‘chameleon’ peptide in proteins, i.e., whether it is observed as a helix in strand, helix in coil, strand in coil , strand in helix, coil in helix or coil in strand, in any of the proteins in the PDB. In each case, the first conformation refers to that of the ‘probe’ peptide sequence and the second conformation refers to that of the ‘target’ peptide sequence.

CHAMPEP-SLIDING is available at: http://203.200.217.185/chameleon/sliding.php