Overview of Research Areas
- Genome organization and epigenetic regulation
- Theoretical studies of biological systems
- Analysis of protein structure and function using Protein Contact Networks.
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Development of simple and computationally inexpensive alignment-free methods for
classification based on genomic heterogeneity using Chaos Game Representation and
Multi-fractal analysis.
- Studying host-parasite co-evolution using genome sequence analysis of HIV-1.
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Comparative genomic analysis of evolution of metabolic pathways and horizontal gene
transfer in prokaryotes.
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Modelling feedback regulatory processes in biochemical pathways using "gene circuits",
and the dynamical effects of noise.
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Large scale reconstruction and analysis of metabolic pathways using graph theory and
optimisation techniques in health and disease.
- Understanding collective behaviour in multi-cell systems using physical principles.
- Studying disease prevalence in populations using mathematical and statistical modelling.
- Homology modeling of serotonin receptor
- Affibody engineered for cell-specific nucleic acid targeting
- Structural bioinformatics
- Towards understanding the mechanism of Type III Polyketide Synthases.
- Bioinformatics of proteins involved in lipid metabolism in Mycobacterium tuberculosis.
- Bioinformatic Studies on a Unique Cell Wall-Degrading Esterase.
- Bioinformatic analysis on archael tRNA synthetases.
- Sequence-Structure Relatedness in Proteins
- Protein Sequence-Structure Analysis Relational Database.
- Conformations of Hexapeptide and Large Continuous Single Amino Acid Repeats in Proteins.
- Certain Heptapeptide and Large Chameleon Sequences in Proteins.
- Amino Acid Periodicity Peptides in Proteins.
- Disulphide Bridged Connectivity Patterns in Proteins.
- Analysis and the Conformations of Short Intra-Chain Disulphide Bridged Peptides in Proteins.
- Heteroatom Groups and their Neighbors in Proteins.
- Analysis, Detection and the Prediction of Structural Motifs in Proteins.
- Database of Structural Motifs in Proteins.
- Protein Three-dimensional Models
- Plasmepsin V of Plasmodium falciparum.
- IspC protein coding genes from the genomes representing bacterial sub-groups.
- Corynemycolyltransferases in C.glutamicum and C.efficiens.
- C-terminal domain of human alpha-A and alpha-B crystallins.
- Functional Genomics