We combine biophysical, molecular biological and cell biological approaches to address problems of biomedical importance.
Recent Publications
Bakthisaran R, Tangirala R, Rao CM. Small heat shock proteins: Role in cellular functions and pathology. Biochim Biophys Acta. 2014 Dec 30.
Das T, Volety S, Ahsan SM, Thakur AK, Sharma S, Padhi TR, Basu S, Rao CM. Safety, sterility and stability of direct-from-vial multiple dosing intravitreal injection of bevacizumab.Clin Experiment Ophthalmol. 2014 Dec 29.
Micheal IJ, Vidyasagar AJ, Bokara KK, Mekala NK, Asthana A, Rao ChM. Foil assisted replica molding for fabrication of microfluidic devices and their application in vitro.Lab Chip. 2014 Oct 7;14(19):3695-9.
Bokara KK, Oggu GS, Vidyasagar AJ, Asthana A, Lee JE, Rao ChM. Modulation of stem cell differentiation by the influence of nanobiomaterials/carriers.Curr Stem Cell Res Ther. 2014;9(6):458-68.
Asthana A, Bollapalli M, Tangirala R, Bakthisaran R, Mohan Rao Ch. Hsp27 suppresses the Cu(2+)-induced amyloidogenicity, redox activity, and cytotoxicity of α-synuclein by metal ion stripping. Free Radic Biol Med. 2014 Jul;72:176-90.
Swamy-Mruthinti S, Srinivas V, Hansen JE, Rao ChM. Thermal Stress Induced Aggregation of Aquaporin 0 (AQP0) and Protection by α-Crystallin via Its Chaperone Function.PLoS One. 2013 Nov 27;8(11):e80404.
Sultan A, Raman B, Rao ChM, Tangirala R. The Extracellular Chaperone Haptoglobin Prevents Serum Fatty Acid-promoted Amyloid Fibril Formation of β2-Microglobulin, Resistance to Lysosomal Degradation, and Cytotoxicity. J Biol Chem. 2013 Nov 8;288(45):32326-42.
Karunakaran SC, Babu PS, Madhuri B, Marydasan B, Paul AK, Nair AS, Rao KS, Srinivasan A, Chandrashekar TK, Rao CM, Pillai R, Ramaiah D. In vitro Demonstration of Apoptosis Mediated Photodynamic Activity and NIR Nucleus Imaging through a Novel Porphyrin. ACS Chem Biol. 2013 Jan 18;8(1):127-32.