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Biological systems engineer unique geometrical architectures poised for function. With extreme biophysics as our lens and bio-diversity as our playground - here I will highlight a few examples of extr...
Our research program stems from a long standing interest in understanding the principles of self-organization in complex systems out of equilibrium. Starting from studies on the physics of collective ...
Transcription regulation is a key component of cell identity and function. In this seminar, I will discuss how transcription programs are maintained through the cell cycle, and explore new mechanisms ...
Tigers are among the most charismatic species on earth. Two thirds of all tigers live in India, alongside 1.3 billion people. We have spent the last fifteen years understanding genetic connectivity an...
The perception of time intervals between events dictates many behaviors. However, the neural mechanisms that mediate our ability to discriminate time intervals are not yet clearly understood. In my ta...
Synthetic biology is bringing together engineers, physicists and biologists to model, design and construct biological circuits out of proteins, genes and other bits of DNA, and to use these circuits t...
New therapies that promote antitumor immunity have been recently developed. Most of these immunomodulatory approaches have focused on enhancing T-cell responses, either by targeting inhibitory pathway...
To investigate the formation and role of ordered membrane domains (lipid rafts) we developed a phospholipid exchange method using cyclodextrins to prepare artificial lipid vesicles with asymmetry mimi...
In biology, the search for molecular mechanisms for organismal traits is often likened to the quest for the Holy Grail. I will argue that such mechanisms are mostly illusions, perhaps like the grail i...
Seeds are a key stage in the plant life cycle. The endosperm, a nutritive seed tissue, is essential for seed viability. Endosperm is also home to a fascinating epigenetic phenomenon, gene imprinting. ...
This talk will revolve around two well-known sayings. The first is “All biology is chemistry and all chemistry is physics”. It is interpreted to mean that (a) chemical phenomena are based on the p...
Ubiquitylation is essential for cell fate specification in all eukaryotes, and mutations in ubiquitylation enzymes are often the cause of severe disease. We have identified several ubiquitin-dependent...
The human genome contains just 825 megabytes of information, yet programs the precise ontogeny of an organism that can walk and talk. Most of the genome is differentially transcribed during developmen...
Common people and even scientists think of ecology as a discipline that exclusively studies wildlife and topics related to environmental pollution. My friends both within and outside the scientific co...
In this presentation, Dr. Sam Illingworth will explore how poetry and games can be used to move away from one-way methods of communication and towards two-way dialogue between scientists and non-scien...
Cellular differentiation is a complex process. Transitions from a stem to differentiated state require control of gene expression at transcriptional, post-transcriptional and translation level. Studyi...
C. elegans can transmit certain responses transgenerationally, however it is unknown whether these can impact the process of evolution. Here, by studying nematodes that choose whether to self-reproduc...
Polyneuropathy, Hearing loss, Ataxia, Retinitis pigmentosa, and Cataract (PHARC) is an autosomal recessive human genetic neurological disorder caused by deleterious (null) mutations to the abhd12 gene...
The human brain exhibits a number of unique characteristics, such as dramatic size expansion and variation in relative abundance of specific neuron populations. In an effort to better understand human...
We recently introduced new tools for high-resolution genome-wide chromatin profiling and have applied them to study chromatin organization and dynamics in a variety of model systems, including yeast, ...
In the last ten years electron cryotomography (cryo-ET) has made it possible to visualize large macromolecular assemblies inside intact cells in a near-native, "frozen-hydrated" state in 3-D to a few ...
CREDITS:
SudiptaMondal (Logo design)
Manish Bhattacharjee (Series name)
Renu Sudhakar & Santosh Kumar Kuncha (Concept)All rights © CSIR-CCMB