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ARCHIVED TALKS

18 Jan 2023

Janet Iwasa

Animating Molecular Machines

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06 Sep 2022

Philip Rosenthal

Antimalarial drug resistance in Africa

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17 Aug 2022

Manu Prakash

Topological puzzles in cell biology: How geometry shapes cellular form

Biological systems engineer unique geometrical architectures poised for function. With extreme biophysics as our lens and bio-diversity as our playground - here I will highlight a few examples of extr...


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28 Apr 2022

Shashi Thutupalli

Towards synthetic biology from a physical perspective

Our research program stems from a long standing interest in understanding the principles of self-organization in complex systems out of equilibrium. Starting from studies on the physics of collective ...


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23 Mar 2022

Sheila Teves

Transcriptional memory and dynamics in embryonic stem cells

Transcription regulation is a key component of cell identity and function. In this seminar, I will discuss how transcription programs are maintained through the cell cycle, and explore new mechanisms ...


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18 Feb 2022

Uma Ramakrishnan

How does genetic data inform tiger conservation?

Tigers are among the most charismatic species on earth. Two thirds of all tigers live in India, alongside 1.3 billion people. We have spent the last fifteen years understanding genetic connectivity an...


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28 Jan 2022

Fiona Watt

Understanding the cell heterogeneity in multi-layered epithelia

Advances in single cell technologies such as RNA-sequencing provide new opportunities to understand the cellular heterogeneity of different tissues. The Human Cell Atlas is a global initiative to crea...


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18 Jan 2022

Vatsala Thirumalai

Follow the beat: Brain mechanisms for learning time intervals

The perception of time intervals between events dictates many behaviors. However, the neural mechanisms that mediate our ability to discriminate time intervals are not yet clearly understood. In my ta...


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17 Nov 2021

James J Collins

Synthetic biology - life redesigned

Synthetic biology is bringing together engineers, physicists and biologists to model, design and construct biological circuits out of proteins, genes and other bits of DNA, and to use these circuits t...


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25 Oct 2021

Eric Vivier

Harnessing innate immunity in cancer therapy

New therapies that promote antitumor immunity have been recently developed. Most of these immunomodulatory approaches have focused on enhancing T-cell responses, either by targeting inhibitory pathway...


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16 Sep 2021

Erwin London

Using Lipid Exchange to Understand Membrane Organization and Function

To investigate the formation and role of ordered membrane domains (lipid rafts) we developed a phospholipid exchange method using cyclodextrins to prepare artificial lipid vesicles with asymmetry mimi...


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14 Jul 2021

Amitabh Joshi

The illusion of mechanism in biology

In biology, the search for molecular mechanisms for organismal traits is often likened to the quest for the Holy Grail. I will argue that such mechanisms are mostly illusions, perhaps like the grail i...


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15 Jun 2021

Mary Gehring

Genetic Conflicts and Seed Biology

Seeds are a key stage in the plant life cycle. The endosperm, a nutritive seed tissue, is essential for seed viability. Endosperm is also home to a fascinating epigenetic phenomenon, gene imprinting. ...


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31 May 2021

Vidyanand Nanjundiah

To what extent are physics and chemistry sufficient to account for biology?

This talk will revolve around two well-known sayings. The first is “All biology is chemistry and all chemistry is physics”. It is interpreted to mean that (a) chemical phenomena are based on the p...


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13 May 2021

Michael Rape

Ubiquitin-dependent control of development and disease

Ubiquitylation is essential for cell fate specification in all eukaryotes, and mutations in ubiquitylation enzymes are often the cause of severe disease. We have identified several ubiquitin-dependent...


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19 Apr 2021

John Mattick

Genomes: The .zip files of transcriptomes

The human genome contains just 825 megabytes of information, yet programs the precise ontogeny of an organism that can walk and talk. Most of the genome is differentially transcribed during developmen...


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11 Mar 2021

Vishwesha Guttal

The Physics of Ecology: Fundamental Parallels Between Statistical Physics and Ecology

Common people and even scientists think of ecology as a discipline that exclusively studies wildlife and topics related to environmental pollution. My friends both within and outside the scientific co...


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12 Feb 2021

Sam Illingworth

Poetry of Science: Using poetry and games to develop dialogue between scientists and non-scientists

In this presentation, Dr. Sam Illingworth will explore how poetry and games can be used to move away from one-way methods of communication and towards two-way dialogue between scientists and non-scien...


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28 Jan 2021

Dasaradhi Palakodeti

tRNA derived small RNA fragments: their biogenesis and function in stem cells

Cellular differentiation is a complex process. Transitions from a stem to differentiated state require control of gene expression at transcriptional, post-transcriptional and translation level. Studyi...


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23 Nov 2020

Oded Rechavi

C.elegans Parental Experiences Regulate a Critical Decision Made by the Progeny

C. elegans can transmit certain responses transgenerationally, however it is unknown whether these can impact the process of evolution. Here, by studying nematodes that choose whether to self-reproduc...


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16 Oct 2020

Siddhesh Kamat

A chemical biology approach towards understanding a human neurological disorder

Polyneuropathy, Hearing loss, Ataxia, Retinitis pigmentosa, and Cataract (PHARC) is an autosomal recessive human genetic neurological disorder caused by deleterious (null) mutations to the abhd12 gene...


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18 Sep 2020

Madeline Lancaster

Examining human brain structure and function with cerebral organoids

The human brain exhibits a number of unique characteristics, such as dramatic size expansion and variation in relative abundance of specific neuron populations. In an effort to better understand human...


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10 Aug 2020

Steven Henikoff

Genome-wide mapping of protein-DNA interaction dynamics

We recently introduced new tools for high-resolution genome-wide chromatin profiling and have applied them to study chromatin organization and dynamics in a variety of model systems, including yeast, ...


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09 Jul 2020

Grant Jensen

Electron cryotomography and the ultrastructure of cells

In the last ten years electron cryotomography (cryo-ET) has made it possible to visualize large macromolecular assemblies inside intact cells in a near-native, "frozen-hydrated" state in 3-D to a few ...


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